Standard Clodrosome Macrophage Depletion Reagents

 

  • Unmodified multilamellar clodronate-containing and control liposomes
  • Composed of biosimilar egg-derived phophatidylcholine and cholesterol in a 7:3 molar ratio
  • Suspended in physiologically-compatible Phosphate Buffered Saline (PBS) at pH 7.4
  • Similar to formulations used in majority of published macrophage depletion studies
  • Optimal size (0.3-3 µm) for rapid macrophage uptake
  • May be dosed systemically or locally (see Routes of Administration )
  • Use Fluoroliposome™ (fluorescent control liposomes) for FACS analysis, confocal microscopy and biodistribution
  • See the FAQ page for more information on the use of fluorescent liposomes in macrophage depletion studies
  • Purchase individual reagents or select a Macrophage Depletion Kit as shown below
  • Most practical and economical choice unless targeting mannose receptors (see Mannosylated Clodrosome Reagents )

Standard Macrophage Depletion Kit

The kit contains one vial of Clodrosome and one vial of Encapsome

The kit contains one vial of Clodrosome and one vial of Encapsome

The Standard Macrophage Depletion Kit contains Clodrosome® (liposomal clodronate) and Encapsome® (control liposomes).

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Fluorescent-DiI Macrophage Depletion Kit

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiI

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiI

The Fluorescent Macrophage Depletion Kit contains Clodrosome® (liposomal clodronate) and Fluoroliposome®-DiI (fluorescent control liposomes).

More Info

 

 

 

Fluorescent-DiO Macrophage Depletion Kit

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiO

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiO

The Fluorescent Macrophage Depletion Kit contains Clodrosome® (liposomal clodronate) and Fluoroliposome®-DiO (fluorescent control liposomes).

More Info

 

 

 

 

 

Fluorescent-DiD Macrophage Depletion Kit

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiD

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiD

The Fluorescent Macrophage Depletion Kit contains Clodrosome® (liposomal clodronate) and Fluoroliposome®-DiD (fluorescent control liposomes).

More Info

 

 

 

 Full Macrophage Depletion Kit with Fluoroliposome®-DiI

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome-DiI

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome-DiI

The Full Macrophage Depletion Kit with Fluoroliposome®-DiI contains Clodrosome® (liposomal clodronate), Encapsome® (control liposomes), and Fluoroliposome®-DiI (fluorescent control liposomes).

More Info

 

 

 

 

 

Full Macrophage Depletion Kit with Fluoroliposome®-DiO

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome®-DiO

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome-DiO

The Full Macrophage Depletion Kit with Fluoroliposome®-DiO contains Clodrosome® (liposomal clodronate), Encapsome® (control liposomes), and Fluoroliposome®-DiO (fluorescent control liposomes).
More Info

 

 

 

 

 

 Full Macrophage Depletion Kit with Fluoroliposome®-DiD

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome-DiD

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome-DiD

The Full Macrophage Depletion Kit with Fluoroliposome®-DiD contains Clodrosome® (liposomal clodronate), Encapsome® (control liposomes), and Fluoroliposome®-DiD (fluorescent control liposomes).

More Info

 

 

 

 

 

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Mannosylated Clodrosome Reagents