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m-Encapsome

 

 

Used for…

  • Assessing the effect of liposomes alone on target phagocytes in m-Clodrosome studies (liposome control)
  • Determining if unexpected results are due to the presence of liposomes rather than clodronate
  • Pretreating to accomplish RES loading which will dramatically alter the distribution and circulation time of subsequently dosed m-Clodrosome
  • Mixing with unencapsulated clodronate to assess the effect of free clodronate in the presence of liposomes

 

Mannosylated control liposomes

Mannosylated control liposomes

Contains: mg/ml mM
L-α-Phosphatidylcholine 18.8 24
Cholesterol 4.2 11
4-Aminophenyl-alpha-D-Mannopyranoside 1 3.69
Suspended in Phosphate Buffered Saline at pH 7.4

See Encapsome Product Description for complete listing of Encapsome properties.

 

 


» Surface-modified with branched-chain oligomannose for optimal recognition by mannose-receptors (MR, SIGNR1)
» Lipid composition is biosimilar egg-phosphatidylcholine and cholesterol in a 7:3 molar ratio
» Optimal size range (0.3-3 µm) for immediate phagocyte recognition and phagocytosis
» Extruded through 2 µm membranes to ensure that liposomes easily pass through lung capillaries
» Prepared and packaged under sterile conditions in 5 ml stoppered glass vials with multidose adapters
» Batches prepared weekly to ensure maximal shelf-life after receipt by client
» Available as single product or in convenient Mannosylated Macrophage Depletion Kits


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Contact

Encapsula NanoSciences LLC
6 Cadillac Dr
Suite 245
Brentwood, TN 37027
Phone: 1-800-387-0620
Phone: 1-800-401-5140
Fax: 615-250-8747
URL: www.encapsula.com
email: info@encapsula.com

Copyright

Clodrosome®, Encapsome®, and Fluoroliposome® are trademarks of Encapsula NanoSciences. The content of the website can only be used by researchers, educators and students for educational purposes. Any commercial use of the content of the website is legally prohibited by the laws of the United States of America.

Disclaimer

All the products sold on the website are for research purposes only. Any use of these products in humans or animals/ pets for treatment purposes is legally prohibited by U S Food and Drug Administration.