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m-Clodrosome

 

Use instead of Clodrosome when…

  • Target phagocyte subset is not being sufficiently depleted by standard Clodrosome
  • Target phagocytes are known to express a mannose receptor (MR, MMR or CD206) or SIGNR1

 

Contains: mg/ml mM
Clodronate Disodium Salt 5 17
L-α-Phosphatidylcholine 18.8 24
Cholesterol 4.2 11
Man3-Glutaryl-Phosphatidylethanolamine 2.1 1.8
Suspended in Phosphate Buffered Saline at pH 7.4
Clodronate Structure

See Clodrosome Product Description for complete listing of clodronate properties.

 

Man3-glu-DPPEMan3-glutaryl-phosphatidylethanolamine is the phospholipid derivative which displays the branched mannose structure on the surface of the liposome.


» Surface-modified with branched-chain oligomannose for optimal recognition by mannose-receptors (MR, SIGNR1)
» Lipid composition is biosimilar egg-phosphatidylcholine and cholesterol in a 7:3 molar ratio
» Optimal size range (0.3-3 µm) for immediate phagocyte recognition and phagocytosis
» Extruded through 2 µm membranes to ensure that liposomes easily pass through lung capillaries
» Prepared and packaged under sterile conditions in 5 ml stoppered glass vials with multidose adapters
» Batches prepared weekly to ensure maximal shelf-life after receipt by client
» Available as single product or in convenient Mannosylated Macrophage Depletion Kits


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Contact

Encapsula NanoSciences LLC
6 Cadillac Dr
Suite 245
Brentwood, TN 37027
Phone: 1-800-387-0620
Phone: 1-800-401-5140
Fax: 615-250-8747
URL: www.encapsula.com
email: info@encapsula.com

Copyright

Clodrosome®, Encapsome®, and Fluoroliposome® are trademarks of Encapsula NanoSciences. The content of the website can only be used by researchers, educators and students for educational purposes. Any commercial use of the content of the website is legally prohibited by the laws of the United States of America.

Disclaimer

All the products sold on the website are for research purposes only. Any use of these products in humans or animals/ pets for treatment purposes is legally prohibited by U S Food and Drug Administration.