Mannosylated Clodrosome Macrophage Depletion Reagents

 

  • Unmodified multilamellar clodronate-containing and control liposomes
  • Composed of biosimilar egg-derived phophatidylcholine and cholesterol in a 7:3 molar ratio
  • 4-Aminophenyl-alpha-D-Mannopyranoside incorporated into the liposomes
  • Suspended in physiologically-compatible Phosphate Buffered Saline (PBS) at pH 7.4
  • Similar to formulations used in majority of published macrophage depletion studies
  • Optimal size (0.3-3 µm) for rapid macrophage uptake
  • May be dosed systemically or locally (see Routes of Administration )
  • Use Fluoroliposome™ (fluorescent control liposomes) for FACS analysis, confocal microscopy and biodistribution
  • See the FAQ page for more information on the use of fluorescent liposomes in macrophage depletion studies
  • Purchase individual reagents or select a Macrophage Depletion Kit as shown below

Mannosylated Macrophage Depletion Kit

The kit contains one vial of Clodrosome and one vial of Encapsome

The kit contains one vial of m-Clodrosome and one vial of m-Encapsome

The Mannosylated Macrophage Depletion Kit contains m-Clodrosome® (liposomal clodronate) and m-Encapsome® (control liposomes).

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Mannosylated Fluorescent-DiI Macrophage Depletion Kit

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiI

The kit contains one vial of m-Clodrosome and one vial of m-Fluoroliposome-DiI

The Mannosylated Fluorescent Macrophage Depletion Kit contains mClodrosome® (liposomal clodronate) and m-Fluoroliposome®-DiI (fluorescent control liposomes).

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Mannosylated Fluorescent-DiO Macrophage Depletion Kit

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiO

The kit contains one vial of m-Clodrosome and one vial of m-Fluoroliposome-DiO

The Mannosylated Fluorescent Macrophage Depletion Kit contains m-Clodrosome® (liposomal clodronate) and m-Fluoroliposome®-DiO (fluorescent control liposomes).

More Info

 

 

 

 

 

Mannosylated Fluorescent-DiD Macrophage Depletion Kit

The kit contains one vial of Clodrosome and one vial of Fluoroliposome-DiD

The kit contains one vial of m-Clodrosome and one vial of m-Fluoroliposome-DiD

The Mannosylated Fluorescent Macrophage Depletion Kit contains m-Clodrosome® (liposomal clodronate) and m-Fluoroliposome®-DiD (fluorescent control liposomes).

More Info

 

 

 

 Full Manosylated Macrophage Depletion Kit with m-Fluoroliposome®-DiI

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome-DiI

The kit contains one vial of m-Clodrosome, one vial of m-Encapsome, and one vial of m-Fluoroliposome-DiI

The Full Mannosylated Macrophage Depletion Kit with m-Fluoroliposome®-DiI contains m-Clodrosome® (liposomal clodronate), m-Encapsome® (control liposomes), and m-Fluoroliposome®-DiI (fluorescent control liposomes).

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Full Mannosylated Macrophage Depletion Kit with m-Fluoroliposome®-DiO

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome®-DiO

The kit contains one vial of m-Clodrosome, one vial of m-Encapsome, and one vial of m-Fluoroliposome-DiO

The Full Mannosylated Macrophage Depletion Kit with m-Fluoroliposome®-DiO contains m-Clodrosome® (liposomal clodronate), m-Encapsome® (control liposomes), and m-Fluoroliposome®-DiO (fluorescent control liposomes).
More Info

 

 

 

 

 

 Full Mannosylated Macrophage Depletion Kit with m-Fluoroliposome®-DiD

The kit contains one vial of Clodrosome, one vial of Encapsome, and one vial of Fluoroliposome-DiD

The kit contains one vial of m-Clodrosome, one vial of m-Encapsome, and one vial of m-Fluoroliposome-DiD

The Full Mannosylated Macrophage Depletion Kit with m-Fluoroliposome®-DiD contains m-Clodrosome® (liposomal clodronate), m-Encapsome® (control liposomes), and m- Fluoroliposome®-DiD (fluorescent control liposomes).

More Info

 

 

 

 

 

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Standard Clodrosome Reagents